BioGlue is the leading surgical adhesive used in cardiovascular surgery worldwide; it has been used in over 750,000 surgical procedures since its launch in 1998. BioGlue is two components, purified bovine serum albumin (BSA) and Glutaraldehyde, which are dispensed by a controlled delivery system. Once dispensed, the two components are fully mixed within the applicator tip. BioGlue, upon application to the tissue at the repair site, creates a flexible mechanical seal independent of the body’s clotting mechanisms. BioGlue begins to polymerize within 20 to 30 seconds and reaches full strength within two minutes. BioGlue also adheres to synthetic graft materials through mechanical bonding within the interstices of the graft matrix. Bioglue has both FDA &CE approvals.